940286-42-0Relevant academic research and scientific papers
Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria
Hanessian, Stephen,Pachamuthu, Kandasamy,Szychowski, Janek,Gigure, Alexandre,Swayze, Eric E.,Migawa, Michael T.,Fran?ois, Boris,Kondo, Jiro,Westhof, Eric
supporting information; experimental part, p. 7097 - 7101 (2011/01/03)
Incorporation of an hydrophobic (phenethylamino)ethyl ether at C2″ of N1-(HABA)-3′,4′-dideoxyparomomycin led to a novel analog with an excellent antibacterial profile against a host of resistant bacteria.
