940290-22-2

Basic information

• Product Name: N-(3-(4-acetoxyphenyl)-propenoyl)-D-alanine tryptamide
• Synonyms: N-(3-(4-acetoxyphenyl)-propenoyl)-D-alanine tryptamide
• CAS NO: 940290-22-2
• Molecular Weight: 419.48
• Mol File: 940290-22-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-(4-acetoxyphenyl)-propenoyl)-D-alanine tryptamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-(4-acetoxyphenyl)-propenoyl)-D-alanine tryptamide(940290-22-2)
• EPA Substance Registry System: N-(3-(4-acetoxyphenyl)-propenoyl)-D-alanine tryptamide(940290-22-2)

Safety Data

• Hazardous Substances Data: 940290-22-2(Hazardous Substances Data)

Upstream product

• 7400-08-0 p-Coumaric Acid 
• 940290-20-0 N-(benzyloxycarbonyl)-D-alanine tryptamide 
• 940290-21-1 D-alanine tryptamide 
• 27542-85-4 4-acetoxycinnamic acid 

Relevant articles and documents

N-(3-(4-Hydroxyphenyl)-propenoyl)-amino acid tryptamides as SIRT2 inhibitors

A series of N-(3-(4-hydroxyphenyl)-propenoyl)-amino acid tryptamides was based on a previously reported new SIRT2 inhibitor from our group, and it was designed to study if the molecular size of the compound could be reduced. The most potent compounds, N-(3-(4-hydroxyphenyl)-propenoyl)-2-aminoisobutyric acid tryptamide and N-(3-(4-hydroxyphenyl)-propenoyl)-l-alanine tryptamide, were equipotent, 30% smaller in molecular weight, and slightly more selective (SIRT2/SIRT1) than the parent compound.