940291-87-2

Upstream product

• 207226-31-1 1,3-dibromo-5-(trifluoromethoxy)benzene 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 

Downstream Products

• 1124141-65-6 C₉H₆BrF₅O 
• 1124140-87-9 C₉H₅Br₂F₃O₂ 
• 1124142-77-3 1-bromo-3-(tert-butyl)-5-(trifluoromethoxy)benzene 

Relevant academic research and scientific papers

PYRROLO CARBOXAMIDES AS MODULATORS OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (ROR?, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES

The invention provides modulators for the orphan nuclear receptor ROR? and methods for treating ROR? mediated diseases by administrating these novel ROR? modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo carboxamide compounds of Formula (1) and the enantiomers, diastereomers, N-oxides, tautomers, solvates and pharmaceutically acceptable salts thereof.

THIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS

The invention encompasses compounds of Formula I (I) or pharmaceutically acceptable salts thereof, which are antagonist of the CXCR3 chemokine receptor useful for the treatment or prevention of pathogenic inflammatory processes, autoimmune diseases or graft rejection processes. Methods of use and pharmaceutical compositions are also encompassed.