940865-65-6

Basic information

• Product Name: 1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate
• Synonyms: 1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate
• CAS NO: 940865-65-6
• Molecular Weight: 479.93
• Mol File: 940865-65-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate(940865-65-6)
• EPA Substance Registry System: 1,1-dimethylethyl (3S)-3-((3-chloro-4-cyanophenyl){[2-(trifluoromethyl)phenyl]methyl}amino)-1-pyrrolidinecarboxylate(940865-65-6)

Safety Data

• Hazardous Substances Data: 940865-65-6(Hazardous Substances Data)

Upstream product

• 940865-64-5 1,1-dimethylethyl (3S)-3-[(3-chloro-4-cyanophenyl)amino]-1-pyrrolidnecarboxylate 
• 395-44-8 o-trifluoromethylbenzyl bromide 

Downstream Products

• 940862-14-6 2-chloro-4-((3S)-3-pyrrolidinyl{[2-(trifluoromethyl)phenyl]methyl}amino)benzonitrile 

Relevant articles and documents

Improving the developability profile of pyrrolidine progesterone receptor partial agonists

The previously reported pyrrolidine class of progesterone receptor partial agonists demonstrated excellent potency but suffered from serious liabilities including hERG blockade and high volume of distribution in the rat. The basic pyrrolidine amine was in

PYRROLIDINEANILINES

The present invention relates to a compotind represented by the following formula I or a pharmaceutically acceptable salt thereof; wherein R1, R2, and y are defined herein. The present invention further relates to compositions that include the compound of the present invention as well as a method of treating a patient from endometreosis or uterine fibroids.