940880-69-3

Basic information

• Product Name: (S)-7,7Bis[(4S)-(phenyl)oxazol-2-yl)]-2,23,3tetrahydro-1,1spirobiindane, min. 97% (Sa,S,S)-SpiroBOX
• Synonyms: (S)-7,7Bis[(4S)-(phenyl)oxazol-2-yl)]-2,23,3tetrahydro-1,1spirobiindane, min. 97% (Sa,S,S)-SpiroBOX;Oxazole,2,2'-[(1S)-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diyl]bis[4,5-dihydro-4-phenyl-,(4S,4'S)-;(Sa,S,S)-7,7′-bis(4′-phenyloxazol-2-yl)-1,1′-spirobiindane;(R)-7-(4,5-Dihydrooxazol-2-yl)-7′-di(3,5-ditertbutylphenyl)phosphino-1,1′-spirobiinane
• CAS NO: 940880-69-3
• Molecular Formula: C35H30N2O2
• Molecular Weight: 510.6249
• Product Categories: Chiral Spiro Ligand;BOX series;Chiral Nitrogen;Chiral Phosphine;PHOX Series
• Mol File: 940880-69-3.mol

Chemical Properties

• Melting Point: 167-169°C
• Boiling Point: 712.1±60.0 °C(Predicted)
• Appearance: white/solid
• Density: 1.29±0.1 g/cm3(Predicted)
• PKA: 4.12±0.70(Predicted)
• Sensitive: moisture sensitive
• CAS DataBase Reference: (S)-7,7Bis[(4S)-(phenyl)oxazol-2-yl)]-2,23,3tetrahydro-1,1spirobiindane, min. 97% (Sa,S,S)-SpiroBOX(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-7,7Bis[(4S)-(phenyl)oxazol-2-yl)]-2,23,3tetrahydro-1,1spirobiindane, min. 97% (Sa,S,S)-SpiroBOX(940880-69-3)
• EPA Substance Registry System: (S)-7,7Bis[(4S)-(phenyl)oxazol-2-yl)]-2,23,3tetrahydro-1,1spirobiindane, min. 97% (Sa,S,S)-SpiroBOX(940880-69-3)

Safety Data

• Hazardous Substances Data: 940880-69-3(Hazardous Substances Data)

Usage

Reaction

Chiral ligands for copper-catalyzed asymmetric insertions of carbenoids into N–H bond of anilines. Chiral ligands for copper or palladium-catalyzed asymmetric insertions of carbenoids into O–H bond of phenols. Chiral ligands for copper or iron-catalyzed asymmetric insertions of carbenoids into O–H bond of water. Chiral ligands for copper-catalyzed asymmetric insertions of carbenoids into S-H bonds of arylmethylene mercaptans.

Upstream product

• 20989-17-7 (2S)-2-phenylglycinol 
• 223137-87-9 (R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 528521-72-4 (R)-7,7'-bis(trifluoromethanesulfonyloxy)-1,1'-spirobiindane 
• 920985-42-8 (R)-1,1'-spirobiindane-7,7'-dicaboxylic acid 
• 856407-38-0 (R)-1,1'-spirobiindane-7,7'-dicabonitrile 

Relevant articles and documents

Highly enantioselective insertion of carbenoids into N-H bonds catalyzed by copper complexes of chiral spiro bisoxazolines

A highly efficient copper-catalyzed asymmetric insertion of α-diazoesters into N-H bonds has been realized by using chiral spiro bisoxazoline ligands, affording α-amino acid derivatives in high yields with excellent enantioselectivities. Copyright

Copper-catalyzed enantioselective allylic oxidation of acyclic olefins

A copper-catalyzed asymmetric allylic oxidation of acyclic olefins has been developed. By using the complexes of copper and chiral spiro bisoxazoline ligands as catalysts, the oxidation of various acyclic olefins was accomplished with excellent regioselec

Preparation and application of bisoxazoline ligands with a chiral spirobiindane skeleton for asymmetric cyclopropanation and allylic oxidation

A new type of bisoxazoline ligand 4 (abbreviated as SpiroBOX) containing a chiral spirobiindane scaffold were easily prepared in high yields from enantiomerically pure 1,1′-spirobiindane-7,7′-diol (SPINOL) with 1,1′-spirobiindane-7,7′-dicarboxylic acid as