Cas 940943-41-9,thioacetic acid S-(2-{6-[4-(2-dimethylamino-ethoxy)-benzenesulfonylamino]-pyridin-3-yl}-2-oxo-ethyl) ester

940943-41-9

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Basic information

Product Name: thioacetic acid S-(2-{6-[4-(2-dimethylamino-ethoxy)-benzenesulfonylamino]-pyridin-3-yl}-2-oxo-ethyl) ester
Synonyms: thioacetic acid S-(2-{6-[4-(2-dimethylamino-ethoxy)-benzenesulfonylamino]-pyridin-3-yl}-2-oxo-ethyl) ester
CAS NO:940943-41-9
Molecular Formula:
Molecular Weight: 437.541
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: thioacetic acid S-(2-{6-[4-(2-dimethylamino-ethoxy)-benzenesulfonylamino]-pyridin-3-yl}-2-oxo-ethyl) ester(CAS DataBase Reference)
NIST Chemistry Reference: thioacetic acid S-(2-{6-[4-(2-dimethylamino-ethoxy)-benzenesulfonylamino]-pyridin-3-yl}-2-oxo-ethyl) ester(940943-41-9)
EPA Substance Registry System: thioacetic acid S-(2-{6-[4-(2-dimethylamino-ethoxy)-benzenesulfonylamino]-pyridin-3-yl}-2-oxo-ethyl) ester(940943-41-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 940943-41-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 940943-41-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,0,9,4 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 940943-41:
(8*9)+(7*4)+(6*0)+(5*9)+(4*4)+(3*3)+(2*4)+(1*1)=179
179 % 10 = 9
So 940943-41-9 is a valid CAS Registry Number.

940943-41-9Upstream product

10387-40-3 potassium thioacetate

940943-41-9Downstream Products

940943-41-9Relevant academic research and scientific papers

Identification of KD5170: A novel mercaptoketone-based histone deacetylase inhibitor

Payne, Joseph E.,Bonnefous, Celine,Hassig, Christian A.,Symons, Kent T.,Guo, Xin,Nguyen, Phan-Manh,Annable, Tami,Wash, Paul L.,Hoffman, Timothy Z.,Rao, Tadimeti S.,Shiau, Andrew K.,Malecha, James W.,Noble, Stewart A.,Hager, Jeffrey H.,Smith, Nicholas D.

, p. 6093 - 6096 (2008)

We report the identification of KD5170, a potent mercaptoketone-based Class I and II-histone deacetylase inhibitor that demonstrates broad spectrum cytotoxic activity against a range of human tumor-derived cell lines. KD5170 exhibits robust and sustained histone H3 hyperacetylation in HCT-116 xenograft tumors following single oral or iv dose and inhibition of tumor growth following chronic dosing.

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