940958-93-0

Usage

Uses

Used in Pharmaceutical Industry:
2-Fluoro-5-hydrazinylpyridine is used as a building block for the synthesis of pharmaceutical drugs, leveraging its unique structure and functional groups to contribute to the development of new molecules with potential therapeutic applications.
Used in Chemical Industry:
In the chemical industry, 2-Fluoro-5-hydrazinylpyridine serves as a reagent in various chemical processes, taking advantage of its chemical properties to facilitate reactions and syntheses.
Used in Research and Development:
2-Fluoro-5-hydrazinylpyridine is utilized as an important target for research and development, where its potential for creating new molecules with biological activity is explored, paving the way for innovative applications in medicine and other fields.
Used in Agricultural Applications:
2-Fluoro-5-hydrazinylpyridine may be employed as a pesticide or herbicide, capitalizing on its biological activity to control pests and weeds, thereby contributing to more effective and sustainable agricultural practices.

Upstream product

• 1827-27-6 2-fluoro-5-aminopyridine 

Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS

Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT 1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, and G, are defined herein.

Extending the scope of the aza-Fischer synthesis of 4- and 6-azaindoles

Fischer indole cyclization has recently been described as an efficient approach to the synthesis of azaindoles bearing electron-donating groups. We now show that this cascade reaction can be very efficient for the formation of a wider range of 4- and 6-azaindoles by using microwave irradiation. Fischer indole cyclization starting from aminopyridines is a very efficient cascade sequence leading to 4- and 6-azaindoles. The scope of the substituents on the pyridine ring was extended to include halogens and to weakly electron-donating substituents by using microwave irradiation. Copyright

Substituted pyrazoles as novel sEH antagonist: Investigation of key binding interactions within the catalytic domain

A novel series of pyrazole sEH inhibitors is reported. Lead optimization efforts to replace the aniline core are also described. In particular, 2-pyridine, 3-pyridine and pyridazine analogs are potent sEH inhibitors with favorable CYP3A4 inhibitory and microsomal stability profiles.

1, 5-DIHYDRO-PYRAZOLO (3, 4-D) PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS PDE9A MODULATORS FOR THE TEATMENT OF CNS DISORDERS

The invention relates to novel substituted pyrazolopyrimidines. Chemically, the compounds are characterised by general Formula (I): with R1 being phenyl or pyridyl, any of which is substituted with 1 to 4, preferably 1 to 3 substituents X; X in

STEROIDAL [3, 2-C] PYRAZOLE COMPOUNDS, WITH GLUCOCORTICOID ACTIVITY

The present invention provides compounds of formula (I) wherein n, p, R1, R2, X1, X2, X3, X4, X5, R3a, R3b, R4, R5 and R6 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.

SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS

Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.