941-91-3

Usage

Uses

Used in Pharmaceutical Industry:
N-METHYL-3-BROMO-2(1H)-QUINOLINONE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs.
Used in Agrochemical Industry:
N-METHYL-3-BROMO-2(1H)-QUINOLINONE is utilized as an intermediate in the production of agrochemicals, playing a role in the synthesis of substances that aid in crop protection and enhancement.
Used in Organic Synthesis:
N-METHYL-3-BROMO-2(1H)-QUINOLINONE is used as a building block in organic synthesis, facilitating the creation of complex organic molecules for a range of applications.
Used in Research and Development:
It serves as a key component in research and development initiatives, where its unique properties are explored for potential applications in new chemical entities and processes.
Used in Specialty Chemicals Production:
N-METHYL-3-BROMO-2(1H)-QUINOLINONE is used in the production of specialty chemicals, which are often required for specific, high-value applications in various industries.

InChI:InChI=1/C10H8BrNO/c1-12-9-5-3-2-4-7(9)6-8(11)10(12)13/h2-6H,1H3

Upstream product

• 939-16-2 3-bromoquinolin-2-one 
• 74-88-4 methyl iodide 
• 22615-00-5 3-bromoquinoline N-oxide 
• 101870-60-4 3-bromo-2-chloro-quinoline 
• 1263300-33-9 3-bromo-2-chloro-1-methylquinolinium trifluoromethanesulfonate 
• 5332-24-1 3-bromoquinoline 
• 939-16-2 3-Bromcarbostyril 
• 21979-55-5 1-methyl-3-bromoquinolinium iodide 

Downstream Products

• 197524-35-9 2,2-Dimethyl-N-[2-(1-methyl-2-oxo-1,2-dihydro-quinolin-3-yl)-phenyl]-propionamide 
• 114414-78-7 neocryptolepine 
• 197524-37-1 1-methyl-3-(o-aminophenyl)-1H-quinoline-2-one 
• 1041015-14-8 3-[(2-bromophenyl)amino]-1-methylquinolin-2(1H)-one 

Relevant academic research and scientific papers

CRBN LIGANDS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.

An organocatalyst bound α-aminoalkyl radical intermediate for controlled aerobic oxidation of iminium ions

A catalyst bound α-aminoalkyl radical intermediate from iminium is developed to control its formation and reactivity with aerobic oxygen. The influence of the catalyst was demonstrated via the ease of radical intermediate formation and its subsequent reactivity, including the first catalyst-controlled enantioselective aerobic oxidation with a chiral phosphite catalyst.

THIADIAZOLE ANALOGS THEREOF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED-CONDITIONS

The present invention provides a compound of Formula (X) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolo

Highly efficient one-pot synthesis of D-ring chloro-substituted neocryptolepines via a condensation - Pd-catalyzed intramolecular direct arylation strategy

D-ring chloro-substituted neocryptolepines have been synthesized in excellent yield starting from 3-bromo-2-chloro-1-methylquinolinium triflate via a one-pot condensation - Pd-catalyzed intramolecular direct arylation strategy involving chloroanilines. Th

Pd-catalyzed intramolecular direct arylations at high temperature

Pd-catalyzed cyclodehydrohalogenation involving oxidative addition of aromatic C-Br or activated azaheteroaromatic C-Cl bonds and C(sp2)-H activation have been investigated at high reaction temperatures (180-200 °C). This allowed the fast (10-3

A Convenient Synthesis of Two New Indoloquinoline Alkaloids

A concise synthesis of two new indoloquinoline-based alkaloids (1 and 2), isolated from Cryptolepis sanguinolenta, is reported. The palladium-catalyzed cross-coupling reaction of 3-bromoquinoline derivatives with N-pivaloylamino phenylboronic acid gave th

Ultrasound-promoted synthesis of quinolone and isoquinolone derivatives

Quinolinium and isoquinolinium salts are easily oxidized by potassium tert-butylate in tert-butanol under ultrasonic irradiation yielding quinolones and isoquinolones. Compared to the methods previously known, the main advantages of our process are shorter reaction times, easier work-up and good to quantitative yields.