94108-56-2Relevant academic research and scientific papers
Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids
Debergh, J. Robb,Niljianskul, Nootaree,Buchwald, Stephen L.
supporting information, p. 10638 - 10641 (2013/08/23)
A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.
Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
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, (2008/06/13)
The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.
Keratinocyte growth inhibitors and hydroxamic acid derivatives
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Page 25, (2010/02/06)
This invention relates to a keratinocyte-proliferation inhibitor comprising as active ingredient a compound having an activity of inhibiting the solubilization of heparin-binding EGF-like growth factor bound to cell membranes and a compound of the formula (I); or pharmaceutically acceptable salt thereof, wherein R1, R2, R3 are hydrogen atom or alkyl and X is substituted benzene or the like.
METALLOPROTEASE INHIBITORS
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, (2008/06/13)
Compound of formula (I): STR1 in which: m, n, which are identical or different, represent 0, 1 or 2,R 1, R. sub.2, which are identical or different, represent hydrogen, optionally substituted alkyl, aryl, or form with the carbon atom carrying them carbonyl or (C 3-C 7)cycloalkyl,R 3 represents hydrogen, alkyl, hydroxyl or aryl,R 4 represents any of the groups as defined in the description,X represents--SO 2--,--CO--or--SO 2 NH--,R 5 represents optionally substituted alkyl, (C 3-C 7) cycloalkyl, aryl or heterocyclic,A represents an aryl ring or a heterocycle,its isomers as well as its addition salts with a pharmaceutically acceptable acid or base and medicinal products containing the same are useful as metalloprotease inhibitors.
