94119-07-0

Upstream product

• 76419-48-2 methyl 4,6-O-benzylidene-3-O-benzyl-α-D-glucopyranoside 
• 591727-19-4 1-2,5-6 di-O-isopropylidene 3-O-benzyl α(D)gluco-pentoaldofuranose 
• 94119-05-8 Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-6-aminomethyl-4,5-bis-benzyloxy-2-methoxy-tetrahydro-pyran-3-yl ester 
• 94119-06-9 (1R,3S,4S,7R,8R)-7,8-Bis-benzyloxy-3-methoxy-2-oxa-5-aza-bicyclo[2.2.2]octane 
• 501-53-1 benzyl chloroformate 
• 94152-35-9 Trifluoro-methanesulfonic acid (2S,3R,4S,5R,6R)-4,5-bis-benzyloxy-2-methoxy-6-trifluoromethanesulfonyloxymethyl-tetrahydro-pyran-3-yl ester 
• 94160-77-7 methyl 2-O-trifluoromethanesulfonyl-3-O-benzyl-(R)-4,6-O-benzylidene-α-D-glucopyranoside 
• 57783-73-0 methyl 3,4-di-O-benzyl-α-D-glucopyranoside 
• 94160-78-8 methyl 2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-mannopyranoside 

Downstream Products

• 14199-63-4 1-deoxymannojirimycin 
• 94119-08-1 3,4-di-O-benzyl-1,5-dideoxy-1,5-imino-D-mannitol 

Relevant academic research and scientific papers

SYNTHESES OF 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL FROM D-MANNOSE AND D-GLUCOSE

Unambigous enantiospecific syntheses of 1,5-dideoxy-1,5-imino-D-mannitol (LU1, 1-deoxy-mannojirimycin) are reported (i) from D-mannose via hydrogenation of a 5-azido-5-deoxy mannose, and (ii) from D-glucose, in which the key step involves nucleophilic substitution of a trifluoromethanesulphonyl group from C-2 of D-glucose.