94124-39-7

Basic information

• Product Name: TERT-BUTYLMETHOXYPHENYLSILYL BROMIDE
• Synonyms: tert-Butylmethoxyphenylsilyl Bromide;TBMPSIBR;TERT-BUTYLMETHOXYPHENYLBROMOSILANE;TERT-BUTYLMETHOXYPHENYLSILYL BROMIDE;BROMO-TERT-BUTYLMETHOXYPHENYLSILANE;tert-butylmethoxyphenylsilylbromide96+%;tert-Butyl(methoxy)phenylbromosilane, TBMPSiBr;Bromo-tert-butylmethoxyphenylsilane tert-Butylmethoxyphenylbromosilane
• CAS NO: 94124-39-7
• Molecular Formula: C₁₁H₁₇BrOSi
• Molecular Weight: 273.24
• Product Categories: Monoalkoxysilanes;Protection & Derivatization Reagents (for Synthesis);Si (Classes of Silicon Compounds);Silicon Compounds (for Synthesis);Si-O Compounds;Si-X (F, Br, I) Compounds;Synthetic Organic Chemistry
• Mol File: 94124-39-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 80-82 °C0.1 mm Hg
• Flash Point: 106 °C
• Appearance: /
• Density: 1.218 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.00409mmHg at 25°C
• Refractive Index: n20/D 1.516
• Storage Temp.: Refrigerator
• CAS DataBase Reference: TERT-BUTYLMETHOXYPHENYLSILYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYLMETHOXYPHENYLSILYL BROMIDE(94124-39-7)
• EPA Substance Registry System: TERT-BUTYLMETHOXYPHENYLSILYL BROMIDE(94124-39-7)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-21
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 94124-39-7(Hazardous Substances Data)

Usage

General Description

Tert-butylmethoxyphenylsilyl bromide, also known as TBMPB, is an organosilicon compound commonly used in organic synthesis as a protecting group for alcohols and phenols. It is a clear, colorless liquid with a molecular weight of 327.24 g/mol. TBMPB is used in the creation of various pharmaceuticals, agrochemicals, and fine chemicals. It is a versatile reagent that is especially useful in the protection and deprotection of hydroxyl groups in organic synthesis. TBMPB is known for its stability and compatibility with a wide range of reaction conditions, making it a valuable tool in synthetic chemistry.

InChI:InChI=1/C11H17BrOSi/c1-11(2,3)14(12,13-4)10-8-6-5-7-9-10/h5-9H,1-4H3

Upstream product

• 76358-47-9 tert-butyl(methoxy)diphenylsilane 

Downstream Products

• 94124-36-4 3-(tert-Butyl-methoxy-phenyl-silanyloxymethyl)-heptan-4-ol 
• 94124-62-6 tert-Butyl-methoxy-(1-methyl-cyclohexyloxy)-phenyl-silane 
• 94124-60-4 tert-Butyl-(2-isopropyl-5-methyl-cyclohexyloxy)-methoxy-phenyl-silane 
• 94124-63-7 tert-Butyl-methoxy-(2-methyl-cyclohex-1-enyloxy)-phenyl-silane 
• 94124-37-5 tert-butylmethoxyphenylsilyl-α-D glucopyranoside 
• 253329-28-1 5-(tert-Butyl-methoxy-phenyl-silanyloxy)-2-[(3-isopropyl-4-triisopropylsilanyloxy-phenyl)-methoxy-methyl]-1,3-dimethyl-benzene 
• 253329-12-3 [4-(tert-butyl-methoxy-phenyl-silanyloxy)-2,6-dimethyl-phenyl]-(3-isopropyl-4-triisopropylsilanyloxy-phenyl)-methanol 
• 253329-11-2 4-(tert-butyl-methoxy-phenyl-silanyloxy)-2,6-dimethyl-benzaldehyde 
• 253329-10-1 (4-bromo-3,5-dimethyl-phenoxy)-tert-butyl-methoxy-phenyl-silane 
• 303158-57-8 2,2-dimethyl-propionic acid 3,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-9-(tert-butyl-methoxy-phenyl-silanyloxy)-8-methyl-non-7-enyl ester 
• 303158-60-3 2,2-dimethylpropionic acid 2-{(2S,4R,6R)-6-[(R)-(E)-1-(tert-butyldiphenylsilanyl-oxy)-4-(tert-butylmethoxyphenylsilanyloxy)-3-methyl-but-2-enyl]-4-hydroxy-2-methoxy-tetrahydropyran-2-ylmethyl}-oxazol-4-ylmethyl ester 
• 202859-87-8 (4R,6R,7R)-6-(tert-Butyl-dimethyl-silanyloxy)-4-(tert-butyl-methoxy-phenyl-silanyloxy)-7-methyl-oxepan-2-one 
• 94124-61-5 tert-Butyl-methoxy-((2S,4aR,6S,8S,8aR)-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-phenyl-silane 
• 94124-38-6 (6E,8Z)-(S)-10-(tert-Butyl-methoxy-phenyl-silanyloxy)-5-hydroxy-deca-6,8-dienoic acid methyl ester 

Relevant articles and documents

tert-BUTYLMETHOXYPHENYLSILYL ETHER - A NEW SELECTIVE, STABLE ALCOHOL PROTECTING GROUP WITH REMARKABLE LABILITY TO FLUORIDE.

tert-Butylmethoxyphenylsilyl ethers, which can be formed from primary, secondary or tertiary alcohols and tert-butylmethoxyphenylsilyl bromide, are selectively cleaved by fluoride in the presence of other silyl ethers.