94127-17-0Relevant academic research and scientific papers
N-METHYL DERIVATIVES OF 3-AMINOCARBAZOLE
Kyziol, Janusz B.,Daszkiewicz, Zdzislaw
, p. 839 - 847 (2007/10/02)
Methylation of 3-aminocarbazole in presence of sodium hydrogencarbonate yields carbazolyl-3-trimethylammonium iodide, in alkaline media the fourth methyl group is introduced. 3-(N,N-Dimethylamino)-carbazoles were obtained from corresponding methiodides by lithium aluminium hydride reduction or by thermal decomposition.Synthesis of 3-(N-methylamino)-carbazole via tosylamide failed because of 3-(N-methyltosylamino)-9-tosylcarbazole cleaved only one sulfonamide bond.The method involving formylation of 3-aminocarbazole and reduction of the amide gave satisfactory results.
