94142-89-9Relevant academic research and scientific papers
REACTIVITY OF CARBANIONS. XXII. REACTIONS OF ALKALI-METAL SALTS OF CH ACIDS WITH 9-ACETYL-9-CYANOFLUORENE
Solov'yanov, A. A.,Gulyukina, N. S.,Beletskaya, I. P.,Reutov, O. A.
, p. 209 - 212 (2007/10/02)
The reactions of the lithium and cesium derivatives of 9-methyl-, 9-benzyl-, 9-phenyl-, and 9-methoxycarbonylfluorene, 1,3-diphenylindene, and fluoradene with 9-acetyl-9-cyanofluorene in 1,2-dimethoxyethane take place by a mechanism of nucleophilic substitution at the carbonyl group and lead to the formation of the products from acylation of the carbanions and the corresponding alkali-metal salts of 9-cyanofluorene.If there is a small difference between the pKa value of the CH acid conjugate with the carbanion reagent and the pKa value of 9-cyanofluorene, it is possible to measure the equilibrium constant of the reaction.
