94159-35-0Relevant academic research and scientific papers
A method for preparing 2, 4 - dichlorophenoxyacetic acid (by machine translation)
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Paragraph 0078; 0079, (2018/09/08)
The invention provides a 2, 4 - dichlorophenoxyacetic acid preparation method, comprises the following steps, first the polyol and a halogenated acetic acid to carry out the esterification reaction, to obtain halogenated acetate; then the above-mentioned step to obtain the halo acetate with 2, 4 - dichlorophen salt, to obtain 2, 4 - dichlorophenoxy ester; finally in the composite under the action of catalyst, obtained by the above-mentioned step 2, 4 - dichlorophenoxy ester hydrolytic reaction, to obtain 2, 4 - dichloro acid and polyol; the polyol C atoms is greater than or equal to 2 polyol. The invention adjusts the process route, from creative improvement on the basis of, the preparation method, the process is simple, mild condition, hydrolysis few by-products, the product has high purity, the conversion and yield higher, and intermediate halogenated acetate stable, suitable for large-scale industrial production. (by machine translation)
Synthesis of boron cluster lipids: Closo-dodecaborate as an alternative hydrophilic function of boronated liposomes for neutron capture therapy
Lee, Jong-Dae,Ueno, Manabu,Miyajima, Yusuke,Nakamura, Hiroyuki
, p. 323 - 326 (2008/02/03)
(Chemical Equation Presented) We succeeded in the synthesis of the double-tailed boron cluster lipids 4a-c and 5a-c, which have a B 12H11S moiety as a hydrophilic function, by S-alkylation of B12H11SH (BSH) with bromoacetyl and chloroacetocarbamate derivatives of diacylglycerols for a liposomal boron delivery system on neutron capture therapy. Calcein encapsulation experiments revealed that the liposomes, prepared from the boron cluster lipid 4b, DMPC, PEG-DSPE, and cholesterol, are stable at 37°C in FBS solution for 24 h.
