941703-60-2Relevant academic research and scientific papers
Catalytic enantioselective iodoetherification of oximes
Tripathi, Chandra Bhushan,Mukherjee, Santanu
supporting information, p. 8450 - 8453 (2013/09/02)
Organocatalysis: The first catalytic enantioselective iodoetherification of oximes is developed using commercially available N-iodosuccinimide. In the presence of a dihydrocinchonidine-derived thiourea (10 mol %), β,γ-unsaturated oximes undergo facile iodoetherification to produce Δ2-isoxazolines containing a quaternary stereogenic center generally in high yield with good to excellent enantioselectivity. Copyright
