941715-53-3Relevant academic research and scientific papers
Synthesis of enantioenriched 2- and 2,6-substituted piperidin-3-ols from α-dibenzylamino aldehydes
Andres, Jose M.,Pedrosa, Rafael,Perez-Encabo, Alfonso
, p. 1803 - 1810 (2008/02/08)
Homochiral α-dibenzylamino aldehydes react with 4-butenylmagnesium bromide in diethyl ether at 0°C to yield anti-β-amino alcohols in excellent yield and dr. These anti diastereoisomers were transformed into enantioenriched 2- and 2,6-substituted 3-piperid
