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3-(2-amino-pyrimidin-4-yl)-benzoic acid, also known as tafenoquine, is a chemical compound with significant antimalarial properties. It has been formulated as a superior alternative to primaquine for the treatment and prevention of malaria, especially targeting Plasmodium vivax infections. Tafenoquine operates by inhibiting the development of the malaria parasite within the liver, thus averting the disease's resurgence in the bloodstream. It is considered more potent and longer-acting than primaquine, positioning it as a valuable asset in malaria control and eradication initiatives. Despite its potential, tafenoquine's association with side effects such as hemolysis in individuals with glucose-6-phosphate dehydrogenase deficiency necessitates ongoing research to delineate its full efficacy and safety profile.

942035-84-9

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942035-84-9 Usage

Uses

Used in Pharmaceutical Industry:
3-(2-amino-pyrimidin-4-yl)-benzoic acid is used as an antimalarial agent for the treatment and prevention of malaria, particularly Plasmodium vivax infections, due to its ability to block the parasite's development in the liver and its longer duration of action compared to primaquine.
Used in Malaria Eradication Efforts:
3-(2-amino-pyrimidin-4-yl)-benzoic acid is utilized as a key component in malaria control strategies, given its potential to be more effective in preventing the re-emergence of the disease in the blood, thereby contributing to global health initiatives aimed at malaria eradication.
Used in Research and Development:
3-(2-amino-pyrimidin-4-yl)-benzoic acid serves as a subject of ongoing research to further understand its efficacy, safety profile, and potential side effects, such as the risk of hemolysis in specific populations, ensuring its safe and effective use in malaria treatment and prevention.

Check Digit Verification of cas no

The CAS Registry Mumber 942035-84-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,0,3 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 942035-84:
(8*9)+(7*4)+(6*2)+(5*0)+(4*3)+(3*5)+(2*8)+(1*4)=159
159 % 10 = 9
So 942035-84-9 is a valid CAS Registry Number.

942035-84-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2-aminopyrimidin-4-yl)benzoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:942035-84-9 SDS

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