942070-74-8

Basic information

• Product Name: 1,2-DiMethyl-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-1H-iMidazole
• Synonyms: 1,2-DiMethyl-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-1H-iMidazole;1,2-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-imidazole
• CAS NO: 942070-74-8
• Molecular Formula: C11H19BN2O2
• Molecular Weight: 222.09176
• Mol File: 942070-74-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 357.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.04±0.1 g/cm3(Predicted)
• PKA: 7.14±0.43(Predicted)
• CAS DataBase Reference: 1,2-DiMethyl-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-1H-iMidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DiMethyl-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-1H-iMidazole(942070-74-8)
• EPA Substance Registry System: 1,2-DiMethyl-5-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-1H-iMidazole(942070-74-8)

Safety Data

• Hazardous Substances Data: 942070-74-8(Hazardous Substances Data)

Usage

Type of compound

boron-containing heterocyclic compound

Use

commonly used as a ligand in organometallic chemistry

Application

used in the synthesis of various coordination complexes and catalysts

Bonding ability

has the ability to form strong bonds with transition metals

Versatility

a versatile building block in the field of organic synthesis

Derivatives

potential applications in pharmaceuticals and materials science

Safety

should be handled with caution due to possible health and environmental hazards

Disposal

proper management and disposal are necessary to minimize risks

Structure

features a 1,3,2-dioxaborolan ring fused to an imidazole core, with methyl groups at the 1 and 2 positions of the imidazole and a tetramethyl group on the dioxaborolan ring.

Upstream product

• 1739-84-0 1,2-dimethyl-1H-imidazole 
• 73183-34-3 bis(pinacol)diborane 

Relevant articles and documents

Enzyme-like Supramolecular Iridium Catalysis Enabling C?H Bond Borylation of Pyridines with meta-Selectivity

The use of secondary interactions between substrates and catalysts is a promising strategy to discover selective transition metal catalysts for atom-economy C?H bond functionalization. The most powerful catalysts are found via trial-and-error screening due to the low association constants between the substrate and the catalyst in which small stereo-electronic modifications within them can lead to very different reactivities. To circumvent these limitations and to increase the level of reactivity prediction in these important reactions, we report herein a supramolecular catalyst harnessing Zn???N interactions that binds to pyridine-like substrates as tight as it can be found in some enzymes. The distance and spatial geometry between the active site and the substrate binding site is ideal to target unprecedented meta-selective iridium-catalyzed C?H bond borylations with enzymatic Michaelis–Menten kinetics, besides unique substrate selectivity and dormant reactivity patterns.

Process for producing oxazole, imidazole, pyrrazole boryl compounds

Process for the preparation of oxazole, imidazole, and pyraxole boryl compounds. The compounds are intermediates to functionalized compounds, both natural and synthetic which are cytotoxic, anticancer and antiviral agents.