942070-84-0

Basic information

• Product Name: 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole
• Synonyms: 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole;5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-oxazole;5-(4,4,5,5-tetramethyl-1,3,2,-dioxaboralan-2-yl)oxazole
• CAS NO: 942070-84-0
• Molecular Formula: C₉H₁₄BNO₃
• Molecular Weight: 195
• Mol File: 942070-84-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 276.7±13.0 °C(Predicted)
• Appearance: /
• Density: 1.08±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 0.58±0.10(Predicted)
• CAS DataBase Reference: 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole(942070-84-0)
• EPA Substance Registry System: 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole(942070-84-0)

Safety Data

• Hazardous Substances Data: 942070-84-0(Hazardous Substances Data)

Usage

Uses

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole is a reagent used in the preparation of checkpoint kinase I (Chk1) inhibitors, used in the treatment of DNA damage and facilitating cell-cycle arrest.

Downstream Products

• 1433884-68-4 (S)-3-(2-fluoro-4-(methylsulfonyl)phenoxy)-1-(1-(3-(oxazol-5-yl)-1,2,4-thiadiazol-5-yl)piperidin-4-yl)pyrrolidin-2-one 
• 1286178-98-0 ethyl 6-(benzenesulphonylmethyl)-2-methoxy-3-(oxazol-5-yl)benzoate 
• 1070162-80-9 2-fluoro-4-(2-(oxazol-5-yl)pyridin-4-yloxy)benzenamine 

Relevant articles and documents

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Process for the preparation of oxazole, imidazole, and pyraxole boryl compounds. The compounds are intermediates to functionalized compounds, both natural and synthetic which are cytotoxic, anticancer and antiviral agents.