942155-29-5Relevant articles and documents
Synthesis of 4-methyldienoates using a vinylogous horner-wadsworth-emmons reagent. application to the synthesis of trichostatic acid
Markiewicz, John T.,Schauer, Douglas J.,Loefstedt, Joakim,Corden, Steven J.,Wiest, Olaf,Helquist, Paul
, p. 2061 - 2064 (2010)
Chemical Equation Presented The utility of the unsaturated phosphonate 1 as a vinylogous Horner-Wadsworth-Emmons reagent was explored in reactions with, aldehydes affording 4-methyldienoate esters. Factors that affect E/Z selectivity were studied. A simplified synthesis of trichostatic acid 3 was accomplished, to demonstrate utility of this reagent.