Cas 942189-48-2,3-amino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester

942189-48-2

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Basic information

Product Name: 3-amino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester
Synonyms: 3-amino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester
CAS NO:942189-48-2
Molecular Formula:
Molecular Weight: 625.731
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-amino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 3-amino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester(942189-48-2)
EPA Substance Registry System: 3-amino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester(942189-48-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 942189-48-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 942189-48-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,1,8 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 942189-48:
(8*9)+(7*4)+(6*2)+(5*1)+(4*8)+(3*9)+(2*4)+(1*8)=192
192 % 10 = 2
So 942189-48-2 is a valid CAS Registry Number.

942189-48-2Upstream product

942189-48-2Downstream Products

942189-49-3 3-acetylamino-5-[(1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]ethyl}-pyrrolidine-3-carbonyl)-amino]-indazole-1-carboxylic acid tert-butyl ester

942189-48-2Relevant academic research and scientific papers

POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS

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Page/Page column 208, (2008/06/13)

Disclosed are the ERK inhibitors of formula 1.0 and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

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