942299-71-0Relevant academic research and scientific papers
Solvent-Free Synthesis of Cyanoformamides from Carbamoyl Imidazoles
Nugent, Jeremy,Campbell, Sarah G.,Vo, Yen,Schwartz, Brett D.
, p. 5110 - 5118 (2017)
A straightforward and solvent-free synthesis of various secondary and tertiary cyanoformamides from carbamoyl imidazoles and TMSCN has been developed. Both cyclic and acyclic carbamoyl imidazoles react smoothly to form the relevant cyanoformamides in excellent yields, often within minutes.
2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors
-
Page/Page column 23, (2008/06/13)
The present invention relates to 2-adamantylurea derivatives of formula I as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) and the use of such compounds for the treatment and prevention of metabolic syndrome, di
