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2-chloroethyl 4-[bis(2-chloroethyl)amino]phenylbutyrate, also known as Chlorambucil 2-Chloroethyl Ester, is a chemical compound derived from Chlorambucil (C325050). It is an alkylating agent with a molecular structure that features a butyrate group attached to a phenyl ring, which is connected to a bis(2-chloroethyl)amino group. 2-chloroethyl 4-[bis(2-chloroethyl)amino]phenylbutyrate has potential applications in the field of oncology due to its alkylating properties.

94236-91-6

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94236-91-6 Usage

Uses

Used in Oncology:
2-chloroethyl 4-[bis(2-chloroethyl)amino]phenylbutyrate is used as a chemotherapy agent for the treatment of chronic lymphocytic leukemia. It functions by alkyating and cross-linking DNA strands, which inhibits DNA replication and transcription, ultimately leading to the death of cancer cells.
As a derivative of Chlorambucil, 2-chloroethyl 4-[bis(2-chloroethyl)amino]phenylbutyrate may also exhibit potential applications in the treatment of other types of cancer, although further research would be required to explore its efficacy and safety in those contexts. Its specific chemical structure may provide advantages in terms of selectivity for cancer cells or improved pharmacokinetics compared to the parent compound, Chlorambucil.

Check Digit Verification of cas no

The CAS Registry Mumber 94236-91-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,2,3 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 94236-91:
(7*9)+(6*4)+(5*2)+(4*3)+(3*6)+(2*9)+(1*1)=146
146 % 10 = 6
So 94236-91-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H22Cl3NO2/c1-2-15(16(21)22-12-9-19)13-3-5-14(6-4-13)20(10-7-17)11-8-18/h3-6,15H,2,7-12H2,1H3

94236-91-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloroethyl 2-[4-[bis(2-chloroethyl)amino]phenyl]butanoate

1.2 Other means of identification

Product number -
Other names 2-CHLOROETHYL 4-[BIS(2-CHLOROETHYL)AMINO]PHENYLBUTYRATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94236-91-6 SDS

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