942499-63-0Relevant academic research and scientific papers
Synthetic study on telomerase inhibitor, D8646-2-6: Synthesis of the key intermediate using Sn(OTf)2 or Sc(OTf)3 mediated aldol-type reaction and stille coupling
Kanai, Akira,Takeda, Yoshifumi,Kuramochi, Kouji,Nakazaki, Atsuo,Kobayashi, Susumu
, p. 495 - 499 (2008/02/01)
The synthesis of the key intermediate (4) in the proposed route to D8646-2-6 is described. The aldol reaction of the carbohydrate-containing pyrone 7 with the aldehyde 6 was accomplished by using LiHMDS and Sc(OTf)3 or Sn(OTf)2. The
