94250-50-7Relevant academic research and scientific papers
ANNULATION OF 2-FORMYL-2-CYCLOHEXENONES BY REACTION WITH ENAMINES
Meyer, Walter L.,Brannon, Michael J.,Merritt, Andrew,Seebach, Dieter
, p. 1449 - 1452 (1986)
3-Methyl-2-pyrrolidino-1-butene reacts with a series of 2-formyl-2-cyclohexenones to give mixtures of 7,7-dimethyl-Δ8-octalin-1,6-diones and 7,7-dimethyl-8-hydroxy-trans-decalin-1,6-diones which are dehydrated by TFA to afford the octalindiones
Annulation of α-Formyl α,β-Unsaturated Ketones by a Michael Addition-Cyclization Sequence. A Versatile Synthesis of Alicyclic Six-Membered Rings.
Meyer, Walter L.,Brannon, Michael J.,Burgos, Celmira da G.,Goodwin, Thomas E.,Howard, Ralph W.
, p. 438 - 447 (2007/10/02)
The potential generality of the annulation sequence shown in Scheme II (10 -> 11 -> 12 -> 13 -> 14/15) has been examined in model systems.Dehydrogenation of α-formylcyclohexanones 11a-d with 1 equiv of DDQ rapidly produces α,β-unsaturated α-formyl ketones
