94252-22-9

Upstream product

• 19995-19-8 4,5,6,7-tetrahydro-4-oxobenzo[b]thiophene oxime 
• 98-59-9 p-toluenesulfonyl chloride 
• 13414-95-4 4-keto-4,5,6,7-tetrahydrothianaphthene 

Downstream Products

• 180339-69-9 4-(2-Chloro-4-nitro-benzoyl)-7-[1-dimethylamino-meth-(E)-ylidene]-4,5,6,7-tetrahydro-thieno[3,2-b]azepin-8-one 
• 276867-98-2 C₁₆H₁₁ClN₄O₃S 
• 276868-00-9 C₁₆H₁₃ClN₄OS 

Relevant academic research and scientific papers

Further characterization of structural requirements for ligands at the dopamine D2 and D3 receptor: Exploring the thiophene moiety

The present study describes the synthesis and in vitro pharmacology of a novel series of dopaminergic agents in which the classical phenylethylamine pharmacophore is replaced by a thienylethylamine moiety. In general, the novel compounds showed a moderate

The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-Aroyl-2,4,5,6-tetrahydropyrazolo-[3,4-d]thieno[3,2-b]azepines

Synthesis and SAR of N-[4-[(4,5-dihydropyrazolo[3,4-d]thieno[3,2-b]azepin-6(2H)-yl)carbonyl]phenyl]be nzamides as arginine vasopressin (AVP) receptor antagonists are discussed. Potent orally active AVP receptor antagonists are produced when the benzamide moiety contains a phenyl group at the 2-position. Similar analogues of 4,6,7,8-tetrahydro-5H-thieno[3,2-b]azepine and VPA-985 are reported. (C) 2000 Elsevier Science Ltd. All rights reserved.