94265-80-2Relevant academic research and scientific papers
Enantioselective synthesis of optically active Bis(β-hydroxy) sulfones through asymmetric hydrogenation of corresponding ketones catalyzed by a chiral cationic ruthenium diamine catalyst
Huang, Xiaofei,Zhao, Min,Li, Naikai,Li, Haiyan,Li, Jie,Wang, Xingwang
, p. 803 - 813 (2014)
Chiral molecules containing sulfonyl and 1,5-diol moieties are useful synthetic blocks for various asymmetric transformations. A protocol has been developed for the enantioselective synthesis of optically active bis(β-hydroxy) sulfones catalyzed by a chiral cationic ruthenium diamine catalyst. A series of bis(β-hydroxy) sulfones have been obtained in excellent yields (up to 99%) with excellent enantioselectivities (up to 99%) as well as good diastereoselectivities (up to 99:1). Chiral molecules containing sulfonyl and 1,5-diol moieties are useful synthetic blocks for various asymmetric transformations. A protocol has been developed for the enantioselective synthesis of optically active bis(β-hydroxy) sulfones catalyzed by a chiral cationic ruthenium diamine catalyst. A series of bis(β-hydroxy) sulfones have been obtained in excellent yields (up to 99%) with excellent enantioselectivities (up to 99%) as well as good diastereoselectivities (up to 99:1). Copyright
