942913-61-3

Basic information

• Product Name: 2-[2-(di-n-propylamino)ethyl]-6-nitro-phenylacetonitrile
• Synonyms: 2-[2-(di-n-propylamino)ethyl]-6-nitro-phenylacetonitrile
• CAS NO: 942913-61-3
• Molecular Weight: 289.378
• Mol File: 942913-61-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[2-(di-n-propylamino)ethyl]-6-nitro-phenylacetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(di-n-propylamino)ethyl]-6-nitro-phenylacetonitrile(942913-61-3)
• EPA Substance Registry System: 2-[2-(di-n-propylamino)ethyl]-6-nitro-phenylacetonitrile(942913-61-3)

Safety Data

• Hazardous Substances Data: 942913-61-3(Hazardous Substances Data)

Upstream product

• 3598-13-8 (4-chlorophenoxy)acetonitrile 
• 97351-96-7 3-nitro-N,N-dipropylbenzeneethanamine 

Relevant articles and documents

Novel process for ropinirole preparation

A method for producing compounds of the formula: Wherein R2 is selected from the group consisting of amino, lower alkylamino, di-lower alkylamino, allylamino, diallylamino, N-lower alkyl-N-allylamino, benzylamino, dibenzylamino, phenethylamino, diphenethylamino, 4-hydroxyphenethylamino or di-(4-hydroxyphenethylamino); comprising: a) reacting with Wittig Reagent to produce wherein R1 is alkoxyl; f) hydrolyzing compound II under acidic conditions to produce g) subjecting compound III to reduction and amination to produce the tertiary amine wherein R2 is as defined above; h) reacting compound IV with 4-chlorophenoxyacetonitrile to create nucleophilic substitution to produce the nitrile compound wherein R2 is as defined above; and i) effecting reduction and hydrolysis in the same step with palladium/C and sodium hydroxide to produce wherein R2 is as defined above.