942998-89-2

Basic information

• Product Name: ethyl 3,5-dichloro-4-[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]benzoate
• Synonyms: ethyl 3,5-dichloro-4-[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]benzoate
• CAS NO: 942998-89-2
• Molecular Weight: 408.238
• Mol File: 942998-89-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 3,5-dichloro-4-[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3,5-dichloro-4-[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]benzoate(942998-89-2)
• EPA Substance Registry System: ethyl 3,5-dichloro-4-[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]benzoate(942998-89-2)

Safety Data

• Hazardous Substances Data: 942998-89-2(Hazardous Substances Data)

Upstream product

• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 17302-82-8 ethyl 3,5-dichloro-4-hydroxybenzoate 

Downstream Products

• 942998-90-5 ethyl 4-[(2-amino)ethoxy]-3,5-dichlorobenzoate 
• 1006584-02-6 C₂₃H₂₈Cl₂N₂O₅ 
• 1006584-01-5 C₂₁H₂₄Cl₂N₂O₅ 
• 1006584-00-4 C₂₀H₂₂Cl₂N₂O₄ 
• 942998-91-6 ethyl 4-[2-(tert-butyloxycarbonylamino)ethoxy]-3,5-dichlorobenzoate 
• 942998-92-7 4-[2-(tert-butyloxycarbonylamino)ethoxy]-3,5-dichlorobenzoic acid 
• 942999-53-3 4-(2-aminoethoxy)-3,5-dichlorobenzoic acid 

Relevant articles and documents

Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator

Fragment-based lead discovery has been applied to urokinase-type plasminogen activator (uPA). The (R)-enantiomer of the orally active drug mexiletine 5 (a fragment hit from X-ray crystallographic screening) was the chemical starting point. Structure-aided