942999-61-3 Usage
Uses
Used in Pharmaceutical Industry:
Bicyclo[2.2.2]octane-1-acetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]is used as a potential pharmaceutical agent for its ability to interact with biological pathways or targets within the body. Its complex structure and functional groups may allow it to modulate or inhibit specific processes, offering therapeutic benefits in various medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Bicyclo[2.2.2]octane-1-acetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]- serves as a valuable research tool for understanding the structure-activity relationships of biologically active molecules. Its unique features, such as the bicyclic structure and the presence of an amino-substituted pyrimidooxazinyl group, can provide insights into the design and optimization of new drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 942999-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,9,9 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 942999-61:
(8*9)+(7*4)+(6*2)+(5*9)+(4*9)+(3*9)+(2*6)+(1*1)=233
233 % 10 = 3
So 942999-61-3 is a valid CAS Registry Number.
InChI:InChI=1/C24H28N4O3/c1-22(2)19(28-18-20(25)26-14-27-21(18)31-22)15-3-5-16(6-4-15)24-10-7-23(8-11-24,9-12-24)13-17(29)30/h3-6,14H,7-13H2,1-2H3,(H,29,30)(H2,25,26,27)
942999-61-3Relevant academic research and scientific papers
Discovery of a potent, selective, and orally efficacious pyrimidinooxazinyl bicyclooctaneacetic acid diacylglycerol acyltransferase-1 inhibitor
Birch, Alan M.,Birtles, Susan,Buckett, Linda K.,Kemmitt, Paul D.,Smith, Graham J.,Smith, Tim J. D.,Turnbull, Andrew V.,Wang, Steven J. Y.
experimental part, p. 1558 - 1568 (2010/01/07)
Inhibition of DGAT-1 is increasingly seen as an attractive mechanism with the potential for treatment of obesity and other elements of the metabolic syndrome. We report here a bicyclooctaneacetic acid derivative in the pyrimidinooxazine structural class o
PYRIMIDO- [4, 5-B] -OXAZINES FOR USE AS DGAT INHIBITORS
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Page/Page column 38, (2008/06/13)
Formula (I). Compounds of formula (I) or salts thereof, wherein A1, and R1 to R5 are as defined in the specification, are DGAT-1 inhibitors and are thereby useful in the treatment of, for example, obesity. Processes to make compounds of formula (I) are also described.
