943026-40-2

Usage

Uses

Used in Pharmaceutical Industry:
3-CHLORO-6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE is used as a building block for the synthesis of pharmaceutical compounds due to its unique heterocyclic structure and functional groups, which can be further modified to create new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 3-CHLORO-6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE is used as a precursor in the development of new agrochemicals, such as pesticides and herbicides. Its heterocyclic nature allows for the design of compounds with targeted biological activity against pests and weeds.
Used in Organic Synthesis:
3-CHLORO-6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE is used as a versatile building block in organic synthesis for the creation of a wide range of organic compounds. Its structural features enable chemists to explore various synthetic pathways and develop new molecules with diverse applications in different fields.

Upstream product

• 1003944-30-6 C₆H₆BrClN₂O₂ 
• 17284-80-9 2-[(3,6-dichloropyridazin-4-yl)oxy]ethan-1-ol 

Downstream Products

• 1071443-56-5 butyl 6,7-dihydro[1,4]dioxino[2,3-c]pyridazine-3-carboxylate 
• 944407-46-9 6,7-Dihydro[1,4]dioxino[2,3-c]pyridazine-3-carbonitrile 
• 1075260-71-7 (S)-3-({4-[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-ylmethyl)amino]-1-piperidinyl}methyl)-10-fluoro-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one benzoate 
• 1075702-28-1 (R)-3-({4-[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-ylmethyl)amino]-1-piperidinyl}methyl)-10-fluoro-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one benzoate 

Relevant academic research and scientific papers

AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS

The present invention relates to azabicyclic (thio)amide compounds and the uses thereof for controlling phytopathogenic microorganisms such as phytopathogenic fungi. It also relates to processes and intermediates for preparing these compounds

Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones

The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.

HETEROCYCLIC COMPOUNDS, IN PARTICULAR 2-OXO-4,4,5,5,6,6,7,7-OCTAHYDROBENZOXAZOLE DERIVATIVES, AND THEIR USE AS ANTIBACTERIAL COMPOUNDS

This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the compounds in treating bacterial infections and in methods of treating bacterial infections.

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases

During the course of our research on the lead optimisation of the NBTI (Novel Bacterial Type II Topoisomerase Inhibitors) class of antibacterials, we discovered a series of tricyclic compounds that showed good Gram-positive and Gram-negative potency. Herein we will discuss the various subunits that were investigated in this series and report advanced studies on compound 1 (GSK945237) which demonstrates good PK and in vivo efficacy properties.

DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES

Bicyclic nitrogen containing compounds and their use as antibacterials.

TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS

Tricyclic nitrogen containing compounds and their use as antibacterials.

TRICYCLIC NITROGEN CONTAINING COMPOUNDS AS ANTIBACTERIAL AGENTS

Tricyclic nitrogen containing compounds and their use as antibacterials. Z1and Z2 are independently selected from CH and N.