94308-43-7Relevant academic research and scientific papers
3',4'-dihydrospiro[piperidine-4,2'-(1'H)quinoline] derivatives as new antioxidant agents with acetylcholinesterase inhibitory property
Kouznetsov, Vladimir V.,Me?ndez, Leonor Y. Vargas,Acevedo, Amner Mun?oz
, p. 710 - 715 (2013/01/09)
In vitro radical-cation scavenging capacity and anti-AChE activities of 19 piperidine derivatives, including dihy-drospiro[piperidine-4,2'(1'H)quinolines] 7-19 and their precursor 4-allyl-4-arylaminopiperidines 1-6 were reported. Their data of bioassays a
An efficient synthesis of new 1-H-4′-methyl-3′,4′-dihydrospiro[piperidine-4,2′(1′H)quinoline] scaffolds
Vargas Méndez, Leonor Y.,Kouznetsov, Vladimir V.
, p. 2509 - 2512 (2008/02/02)
Efficient synthesis of new 3′,4′-dihydrospiro[piperidine-4,2′(1′H)quinolines] by a four step synthetic route based on 1-benzyl-4-piperidone reactivity is reported.
Synthesis and conformational study of 1,2,3,4,5,6,7,8-octahydro-1,6- naphthiridines
Esipova,Borisenko,Terent'ev,Grishina,Herzshuh
, p. 742 - 747 (2007/10/03)
A new class of endocyclic enamines, 1,6-disubstituted 1,2,3,4,5,6,7,8- octahydro-1,6-naphthiridines, was synthesized from 4-piperidone imines by successive subjecting the latter to lithiation with lithium diethylamide, to alkylation with 1-bromo-3-chloropropane, and to intramolecular cyclization. All stages were carried out as a unique process without isolation of the intermediate compounds. A thorough optimization of the process conditions, workup, and product storage was carried out. The conformational study of 1,6-disubstituted 1,2,3,4,5,6,7,8-octahydro-1,6-naphthiridines was performed. Pleiades Publishing, Inc. 2006.
