94309-60-1

Basic information

• Product Name: N,N'-propylidenebis(benzyl carbamate)
• Synonyms: N,N'-propylidenebis(benzyl carbamate)
• CAS NO: 94309-60-1
• Molecular Weight: 342.395
• Mol File: 94309-60-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N'-propylidenebis(benzyl carbamate)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-propylidenebis(benzyl carbamate)(94309-60-1)
• EPA Substance Registry System: N,N'-propylidenebis(benzyl carbamate)(94309-60-1)

Safety Data

• Hazardous Substances Data: 94309-60-1(Hazardous Substances Data)

Upstream product

• 621-84-1 O-benzyl carbamate 
• 123-38-6 propionaldehyde 

Downstream Products

• 1330527-24-6 (1-(benzyloxycarbonylamino)propyl)methylphosphinic acid 
• 14047-23-5 1-aminopropanephosphonic acid 

Relevant articles and documents

Amidoalkylation of hydrophosphoryl compounds

A new mild procedure of the amidoalkylation of hydrophosphoryl compounds in a mixture of acetic anhydride and acetyl chloride was developed as a convenient method of constructing the a-aminophosphoryl fragment of the pseudo-a,a'-dipeptide molecule. The reaction intermediates N,N'-benzylidene- and N,N'-alkylidenebiscarbamates were detected, isolated, and identified. The report presents the results of studying the direct interaction of hydrophosphoryl compounds previously synthesized with biscarbamates in acetic anhydride and other solvents, the influence of the structure of phosphorus component and biscarbamate, and the effect of acid catalysis on the course of this two-component reaction. A new version of the mechanism of the three-component reaction of amidoalkylation of hydrophosphoryl compounds is suggested: it is regarded as a multistage process involving the stage of biscarbamate formation followed by the stage of Arbuzov-type reaction with the intermediate formation of acyliminium cation and P-OAc derivative with trivalent phosphorus. Pleiades Publishing, Ltd., 2011.