1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one, also known as etravirine, is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infection. It functions by inhibiting the HIV-1 reverse transcriptase enzyme, which is essential for the virus's replication. Etravirine is typically prescribed to patients who have developed resistance to other antiretroviral medications and is administered in combination with other HIV medications. It is available in tablet form and is generally well-tolerated, with common side effects including rash, nausea, and headache. Etravirine has demonstrated effectiveness in reducing viral load and improving immune function in HIV-1 infected individuals.
94330-85-5
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Basic information
- Product Name: 1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one
- Synonyms:
- CAS NO:94330-85-5
- Molecular Formula:
- Molecular Weight: 306.388
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one(94330-85-5)
- EPA Substance Registry System: 1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one(94330-85-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 94330-85-5(Hazardous Substances Data)
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94330-85-5 Usage
Uses
Used in Pharmaceutical Industry:1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one is used as an antiretroviral medication for the treatment of HIV-1 infection. It is particularly effective in patients who have developed resistance to other antiretroviral drugs, providing an alternative treatment option to combat the virus.
1. As a component of combination therapy for HIV-1:
Etravirine is used in combination with other HIV medications to enhance the treatment's effectiveness and reduce the likelihood of the virus developing further resistance.
2. For patients with resistance to other antiretroviral medications:
Etravirine serves as a valuable option for individuals who have not responded well to or have developed resistance against other antiretroviral drugs, offering a new line of defense against the virus.
3. To reduce viral load and improve immune function:
Etravirine has been shown to effectively reduce the viral load in HIV-1 infected individuals and improve their immune function, contributing to better health outcomes and quality of life.
Check Digit Verification of cas no
The CAS Registry Mumber 94330-85-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,3,3 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.Calculate Digit Verification of CAS Registry Number 94330-85:
(7*9)+(6*4)+(5*3)+(4*3)+(3*0)+(2*8)+(1*5)=135
135 % 10 = 5
So 94330-85-5 is a valid CAS Registry Number.
94330-85-5Upstream product
94330-85-5Downstream Products
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1-(4-ethyl-phenyl)-thiazolo[3,2-a]quinazolin-5-one
