943313-35-7

Basic information

• Product Name: tert-butyl 4-(6-(N-hydroxycarbamimidoyl)pyrimidin-4-yloxy)phenylcarbamate
• Synonyms: tert-butyl 4-(6-(N-hydroxycarbamimidoyl)pyrimidin-4-yloxy)phenylcarbamate
• CAS NO: 943313-35-7
• Molecular Weight: 345.358
• Mol File: 943313-35-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(6-(N-hydroxycarbamimidoyl)pyrimidin-4-yloxy)phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(6-(N-hydroxycarbamimidoyl)pyrimidin-4-yloxy)phenylcarbamate(943313-35-7)
• EPA Substance Registry System: tert-butyl 4-(6-(N-hydroxycarbamimidoyl)pyrimidin-4-yloxy)phenylcarbamate(943313-35-7)

Safety Data

• Hazardous Substances Data: 943313-35-7(Hazardous Substances Data)

Upstream product

• 943313-34-6 tert-butyl 4-(6-cyanopyrimidin-4-yloxy)phenylcarbamate 

Downstream Products

• 943313-36-8 [4-(6-[1,2,4]oxadiazol-3-yl-pyrimidin-4-yloxy)-phenyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

NOVEL SUBSTITUTED PYRIMIDINYLOXY UREAS USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds and methods useful as inhibitors of protein kinases, including B-Raf and several receptor tyrosine and cytoplasmic tyrosine kinases. The present invention is directed to new substituted pyrimidinyloxy urea compounds of Formulas II, III and IV and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulating of protein kinase activity in a human or animal subject are also provided for the treatment diseases such as cancers.