94347-47-4Relevant articles and documents
Enzymatic Aminolysis and Transamidation Reactions
Gotor, Vicente,Brieva, Rosario,Gonzalez, Carmen,Rebolledo, Francisca
, p. 9207 - 9214 (2007/10/02)
Chiral amides can be obtained from (+/-)-2-chloropropionate esters and a wide range of amines when the reaction is catalyzed by Candida cylindracea lipase.The enantioselection of the enzyme in this aminolysis reaction depends on the substrate and nucleoph
LEWIS ACID MEDIATED AMINOLYSIS OF ESTERS: CONVERSION OF METHYL (S)-(-)-2-CHLOROPROPIONATE TO (S)-(+)-N,N-DIETHYL-2-CHLOROPROPIONAMIDE
Gless, R. D.
, p. 633 - 638 (2007/10/02)
Methyl (S)-(-)-2-chloropropionate 1 is converted to (S)-(+)-N,N-diethyl-2-chloropropionamide 2 in high chemical and optical yield using a Lewis acid/diethylamine reagent.