943539-83-1Relevant academic research and scientific papers
Catalytic and asymmetric Friedel-Crafts alkylation of indoles with nitroacrylates. Application to the synthesis of tryptophan analogues
Sui, Yong,Liu, Li,Zhao, Jun-Ling,Wang, Dong,Chen, Yong-Jun
, p. 5173 - 5183 (2007)
An asymmetric Friedel-Crafts alkylation of indoles with nitroacrylates catalyzed by chiral (4R,5S)-DiPh-BOX (L1)-Cu(OTf)2 complex (10 mol %) has been developed. The reactions provide tryptophan nitro-precursors in moderate diastereoselectivitie
