943587-25-5 Usage
Uses
Used in Pharmaceutical Industry:
S-1-(p-Tosyl)-3-pyrrolidinol is used as an impurity in the synthesis of Darifenacin for the treatment of urinary incontinence. Darifenacin works by blocking the M3 muscarinic acetylcholine receptor, which helps to control involuntary muscle contractions in the bladder.
In the synthesis process, the presence of S-1-(p-Tosyl)-3-pyrrolidinol as an impurity may affect the purity and efficacy of the final product, Darifenacin. Therefore, it is essential to monitor and control the levels of this impurity during the manufacturing process to ensure the safety and effectiveness of the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 943587-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,3,5,8 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 943587-25:
(8*9)+(7*4)+(6*3)+(5*5)+(4*8)+(3*7)+(2*2)+(1*5)=205
205 % 10 = 5
So 943587-25-5 is a valid CAS Registry Number.
943587-25-5Relevant academic research and scientific papers
Amide-Substituted Titanocenes in Hydrogen-Atom Transfer Catalysis
Zhang, Yong-Qiang,Jakoby, Verena,Stainer, Katharina,Schmer, Alexander,Klare, Sven,Bauer, Mirko,Grimme, Stefan,Cuerva, Juan Manuel,Gans?uer, Andreas
supporting information, p. 1523 - 1526 (2016/02/12)
Two new catalytic systems for hydrogen-atom transfer (HAT) catalysis involving the N-H bonds of titanocene(III) complexes with pendant amide ligands are reported. In a monometallic system, a bifunctional catalyst for radical generation and reduction through HAT catalysis depending on the coordination of the amide ligand is employed. The pendant amide ligand is used to activate Crabtree's catalyst to yield an efficient bimetallic system for radical generation and HAT catalysis.
PROCESSES FOR PREPARING DARIFENACIN HYDROBROMIDE
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Page/Page column 38-39, (2008/06/13)
The invention encompasses processes for the preparation of darifenacin hydrobromide.
