94360-72-2

Upstream product

• 58327-74-5 4,6-diphenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 105-39-5 chloroacetic acid ethyl ester 
• 4604-05-1 2-chloro-4,6-diphenyl-pyridine-3-carbonitrile 
• 623-51-8 ethyl 2-sulfanylacetate 

Downstream Products

• 94639-65-3 2-methyl-7,9-diphenyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 
• 143882-89-7 7,9-diphenyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 
• 153705-80-7 3-Amino-4,6-diphenyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-nitro-phenyl)-meth-(E)-ylidene]-hydrazide 
• 153705-76-1 (3-Cyano-4,6-diphenyl-pyridin-2-ylsulfanyl)-acetic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 153705-78-3 3-Amino-4,6-diphenyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 153705-79-4 3-Amino-4,6-diphenyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-chloro-phenyl)-meth-(E)-ylidene]-hydrazide 
• 153705-75-0 (3-Cyano-4,6-diphenyl-pyridin-2-ylsulfanyl)-acetic acid [1-phenyl-meth-(E)-ylidene]-hydrazide 
• 153705-77-2 3-Amino-4,6-diphenyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-phenyl-meth-(E)-ylidene]-hydrazide 
• 153705-89-6 3-amino-4,6-diphenylthieno<2,3-b>pyridine-2-carboxylic acid azide 
• 153705-69-2 (3-cyano-4,6-diphenyl-2-pyridylthio)acetylhydrazine 
• 153705-70-5 3-amino-4,6-diphenylthieno<2,3-b>pyridine-2-carbohydrazide 
• 58327-70-1 2-carbethoxy-3-amino-4,6-diphenylthieno<2,3-b>pyridine 

Relevant academic research and scientific papers

A simple and expedient method for the synthesis of ethyl 3-amino-4,6-diarylthieno[2,3-b]pyridine-2-carboxylate

(Chemical Equation Presented) 2-Chloro-4,6-diarylnicotinonitrile 1 was reacted with ethyl 2-mercaptoacetate 2 to furnish ethyl 2-(3-cyano-4,6- diarylpyridin-2-ylthio)acetate 3 as intermediates. These intermediates were cyclized by Thorpe-Zeigler cyclizati

INTEGRASE INHIBITORS - 2

The present invention provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Compounds of formula (I) are also provided.

Synthesis and reactions of 2-carbethoxy-3-aminothienopyridines

Several pyridothienopyrimidin-4(3H)-ones (V) and 2-methylpyridothienopyrimidin-4(3H)-ones (VI) have been synthesized from novel 2-carbethoxy-3-aminothienopyridines (IV). 2-Carbethoxymethylmercapto-3-cyanopyridine