943738-05-4Relevant articles and documents
Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2
Ho, Ginny D.,Bercovici, Ana,Tulshian, Deen,Greenlee, William J.,Fawzi, Ahmad,Fernandez, Xiomara,McLeod, Robbie L.,Smith Torhan, April,Zhang, Hongtao
, p. 3028 - 3033 (2008/02/02)
A series of 4-[2-(aminomethyl)phenyl]-1-[bis(2-chlorophenyl)methyl]-4-hydroxypiperidine analogs has been identified as nociceptin receptor ligands. These compounds display high affinity and functional activity at the nociceptin receptor. The synthesis and