943767-44-0Relevant academic research and scientific papers
BrettPhos ligand supported palladium-catalyzed C-O bond formation through an electronic pathway of reductive elimination: Fluoroalkoxylation of activated aryl halides
Rangarajan,Singh, Rajendra,Brahma, Raju,Devi, Kavita,Singh, Rishi Pal,Singh,Prasad, Ashok K.
, p. 14218 - 14225 (2014)
We report an unprecedented BrettPhos ligand supported Pd-catalyzed C-O bond-forming reaction of activated aryl halides with primary fluoroalkyl alcohols. We demonstrate that the Phosphine ligand (BrettPhos) possesses the property of altering the mechanistic pathway of reductive elimination from nucleophile to nucleophile. The Pd/BrettPhos catalyst system facilitates the reductive elimination of the oxygen nucleophile through an electronic pathway.
Diamine derivatives as inhibitors of leukotriene A4 hydrolase
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Page/Page column 66, (2010/11/27)
This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9
