94378-00-4Relevant articles and documents
Identification and Structure-Activity Studies of 1,3-Dibenzyl-2-aryl imidazolidines as Novel Hsp90 Inhibitors
Liu, Yajun,Liu, Xiaoxia,Li, Lihong,Dai, Rui,Shi, Meiyun,Xue, Hongyu,Liu, Yong,Wang, Hecheng
supporting information, (2019/06/10)
Hsp90 (Heat shock protein 90) is involved in various processes in cancer occurrence and development, and therefore represents a promising drug target for cancer therapy. In this work, a virtual screening strategy was employed, leading to the identificatio
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone, a Mild Catalyst for the Formation of Carbon-Nitrogen Bonds
Eynde, Jean Jacques Vanden,Delfosse, Florence,Lor, Pascal,Haverbeke, Yves Van
, p. 5813 - 5818 (2007/10/02)
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) catalyzes the preparation of N-tetrahydropyranylbenzazoles, 2-substituted 1,3-diphenylimidazolidines, and N-(arylmethylene)benzene-1,2-diamines.In the latter case, use of one equivalent of DDQ provides a novel one-pot method for the synthesis of 1H-benzimidazoles.
NOVEL SYNTHESES OF HETEROCYCLES WITH N-(1-HALOALKYL)AZINIUM HALIDES PART 1. PREPARATION OF IMIDAZOLIDINES
Eynde, J.-J. Vanden,Mayence, A.,Maquestiau, A.,Anders, E.
, p. 233 - 236 (2007/10/02)
N-(1-Chloroalkyl)pyridinium chlorides, prepared from thionyl chloride, pyridine, and an aldehyde, readily react with N,N'-disubstituted 1,2-ethanediamine to yield imidazolidines under mild and neutral conditions.