943834-50-2Relevant articles and documents
Palladium-Catalyzed Desymmetric Intermolecular C-N Coupling Enabled by a Chiral Monophosphine Ligand Derived from Anthracene Photodimer
Wang, Xin,Liu, Wei-Gang,Liu, Lan-Tao,Yang, Xiao-Di,Niu, Shu,Tung, Chen-Ho,Wu, Li-Zhu,Cong, Huan
, p. 5485 - 5490 (2021)
The development of chiral ligands with privileged scaffolds plays an important role in transition-metal-catalyzed asymmetric reactions. Herein we present anthracene-photodimer-derived chiral monophosphine ligand 1, which features dual chirality and a rigid scaffold. This ligand exhibits remarkable efficiency in Pd-catalyzed desymmetric intermolecular C-N coupling under mild conditions with excellent chemo- and enantioselectivity.
Enantioposition-selective copper-catalyzed azide-alkyne cycloaddition for construction of chiral biaryl derivatives
Osako, Takao,Uozumi, Yasuhiro
supporting information, p. 5866 - 5869 (2015/01/08)
A highly enantioposition-selective copper-catalyzed azide-alkyne cycloaddition (CuAAC) of dialkynes bearing prochiral biaryls has been developed for the construction of 1,2,3-triazoles bearing axially chiral biaryl groups in up to 76% yield and up to 99% ee.
Two aspects of the desymmetrization of selected prochiral aromatic or vinylic dihalides: enantioselective halogen-lithium exchange and prochiral recognition in chiral liquid crystals
Fan, Chun-An,Ferber, Benoit,Kagan, Henri B.,Lafon, Olivier,Lesot, Philippe
experimental part, p. 2666 - 2677 (2009/04/12)
Several classes of prochiral dihalides have been identified as potential candidates for asymmetric halogen-lithium exchange. Bis-aryl compounds 1 and 2, 2,3-dibromonorbornadiene 3, and 1,2-diiodoferrocene 4 were prepared and used as substrates in the asym
