94391-71-6 Usage
Description
(S)-1-methylpyrrolidine-2-carboxamide, also known as Mecamylamine, is a chemical compound that functions as a non-competitive antagonist of the nicotinic acetylcholine receptors. It is characterized by its ability to block these receptors in the brain, which results in the reduction of the activation of reward pathways associated with various forms of addiction.
Uses
Used in Pharmaceutical Industry:
(S)-1-methylpyrrolidine-2-carboxamide is used as an active pharmaceutical ingredient for the treatment of high blood pressure. Its mechanism of action involves blocking the nicotinic acetylcholine receptors, which helps in regulating blood pressure levels.
Used in Addiction Treatment:
(S)-1-methylpyrrolidine-2-carboxamide is used as a potential therapeutic agent for treating addiction to nicotine, alcohol, and other substances. By blocking the nicotinic acetylcholine receptors in the brain, it decreases the activation of reward pathways, thus reducing the cravings and reinforcing effects associated with these addictive substances.
Used in Neurological Research:
(S)-1-methylpyrrolidine-2-carboxamide can be used as a research tool in the study of the nicotinic acetylcholine receptors and their role in various neurological processes, including addiction, cognition, and memory. Its antagonistic properties allow researchers to investigate the functions and interactions of these receptors in a controlled manner.
Check Digit Verification of cas no
The CAS Registry Mumber 94391-71-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,3,9 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 94391-71:
(7*9)+(6*4)+(5*3)+(4*9)+(3*1)+(2*7)+(1*1)=156
156 % 10 = 6
So 94391-71-6 is a valid CAS Registry Number.
94391-71-6Relevant articles and documents
Synthesis and screening of conformationally restricted and conformationally free N-(tertiary aminoalkyl)dithiocarbamic acids and esters as inhibitors of neuronal nitric oxide synthase
Sassaman, Mark B.,Giovanelli, John,Sood, Virendar K.,Eckelman, William C.
, p. 1759 - 1766 (1998)
N-(Tertiary aminoalkyl)dithiocarbamic acids and esters were synthesized and evaluated for their ability to inhibit neuronal nitric oxide synthase. Preliminary results show these compounds are able to act at the binding site for l-arginine and the conformationally restricted esters may have a second site of activity involving the cofactor (6R)-5,6,7,8-tetrahydro-l-biopterin. Copyright (C) 1997 Elsevier Science Ltd.
