943997-55-5Relevant academic research and scientific papers
Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides
Norman, Mark H.,Zhu, Jiawang,Fotsch, Christopher,Bo, Yunxin,Chen, Ning,Chakrabarti, Partha,Doherty, Elizabeth M.,Gavva, Narender R.,Nishimura, Nobuko,Nixey, Thomas,Ognyanov, Vassil I.,Rzasa, Robert M.,Stec, Markian,Surapaneni, Sekhar,Tamir, Rami,Viswanadhan, Vellarkad N.,Treanor, James J. S.
, p. 3497 - 3514 (2007)
The vanilloid receptor-1 (VR1 or TRPV1) is a member of the transient receptor potential (TRP) family of ion channels and plays a role as an integrator of multiple pain-producing stimuli. From a high-throughput screening assay, measuring calcium uptake in
