944052-68-0Relevant academic research and scientific papers
Enantioselective Cycloaddition of Styrenes with Aldimines Catalyzed by a Chiral Magnesium Potassium Binaphthyldisulfonate Cluster as a Chiral Br?nsted Acid Catalyst
Hatano, Manabu,Nishikawa, Keisuke,Ishihara, Kazuaki
, p. 8424 - 8427 (2017/07/06)
A chiral magnesium potassium binaphthyldisulfonate cluster, as a chiral Br?nsted acid catalyst, was shown to catalyze an enantioselective cycloaddition of styrenes with aldimines for the first time. The strong Br?nsted acidity of the catalyst precursors,
Asymmetric alkylation of N-acylisoindolin-1-ones via α bromoimides: A novel route to 1-substituted isoindolines
Mueller, Andreas,Polborn, Kurt,Wanner, Klaus T.
, p. 575 - 590 (2008/09/16)
(Chemical Equation Presented) Key intermediate in the synthesis of the title compounds 9a-c and 10a-c was the chiral α-bromoimide 1 which has been prepared by radical bromination of the corresponding N-acylisoindolin-1-one 13. 1 was alkylated with silyl enol ethers under Lewis acid catalysis using α-amidoalkylation methodology. N,N-diacyliminium ion 14 is presumably the intermediate in this reaction. Further transformations of the alkylated compounds yielded 1-substituted isoindolines as target compounds.
