944059-24-9 Usage
Uses
Used in Medicinal Chemistry and Drug Discovery:
1H-PYRROLO[2,3-B]PYRIDIN-5-YLBORONIC ACID is used as a ligand for biological targets such as enzymes and receptors, facilitating its role in the development of new pharmaceutical agents.
Used in Sensor and Diagnostic Tool Development:
Leveraging its ability to form stable complexes with diols, 1H-PYRROLO[2,3-B]PYRIDIN-5-YLBORONIC ACID is utilized in the creation of sensors and diagnostic tools that can detect and measure the presence of specific biological molecules.
Used in Pharmaceutical and Materials Science Research:
As a building block in the synthesis of complex organic molecules, 1H-PYRROLO[2,3-B]PYRIDIN-5-YLBORONIC ACID contributes to the advancement of research in both the pharmaceutical industry for drug development and in materials science for the creation of novel materials with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 944059-24-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,0,5 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 944059-24:
(8*9)+(7*4)+(6*4)+(5*0)+(4*5)+(3*9)+(2*2)+(1*4)=179
179 % 10 = 9
So 944059-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BN2O2/c11-8(12)6-3-5-1-2-9-7(5)10-4-6/h1-4,11-12H,(H,9,10)
944059-24-9Relevant academic research and scientific papers
Nickel-catalyzed borylation of halides and pseudohalides with tetrahydroxydiboron [B2(OH)4]
Molander, Gary A.,Cavalcanti, Livia N.,Garcia-Garcia, Carolina
, p. 6427 - 6439 (2013/07/26)
Arylboronic acids are gaining increased importance as reagents and target structures in a variety of useful applications. Recently, the palladium-catalyzed synthesis of arylboronic acids employing the atom-economical tetrahydroxydiboron (BBA) reagent has been reported. The high cost associated with palladium, combined with several limitations of both palladium- and copper-catalyzed processes, prompted us to develop an alternative method. Thus, the nickel-catalyzed borylation of aryl and heteroaryl halides and pseudohalides using tetrahydroxydiboron (BBA) has been formulated. The reaction proved to be widely functional group tolerant and applicable to a number of heterocyclic systems. To the best of our knowledge, the examples presented here represent the only effective Ni-catalyzed Miyaura borylations conducted at room temperature.
