944059-24-9 Usage
General Description
1H-Pyrrolo[2,3-b]pyridin-5-ylboronic acid is a chemical compound with the molecular formula C10H8BNO2. It belongs to the class of boronic acids and contains a pyrrolopyridine ring system. 1H-PYRROLO[2,3-B]PYRIDIN-5-YLBORONIC ACID has potential applications in medicinal chemistry and drug discovery due to its ability to act as a ligand for various biological targets such as enzymes and receptors. Boronic acids are known for their ability to form stable complexes with diols and can be used in the development of sensors and diagnostic tools. Additionally, 1H-Pyrrolo[2,3-b]pyridin-5-ylboronic acid may also be used as a building block in the synthesis of complex organic molecules for pharmaceutical and materials science research.
Check Digit Verification of cas no
The CAS Registry Mumber 944059-24-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,0,5 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 944059-24:
(8*9)+(7*4)+(6*4)+(5*0)+(4*5)+(3*9)+(2*2)+(1*4)=179
179 % 10 = 9
So 944059-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BN2O2/c11-8(12)6-3-5-1-2-9-7(5)10-4-6/h1-4,11-12H,(H,9,10)
944059-24-9Relevant articles and documents
Nickel-catalyzed borylation of halides and pseudohalides with tetrahydroxydiboron [B2(OH)4]
Molander, Gary A.,Cavalcanti, Livia N.,Garcia-Garcia, Carolina
, p. 6427 - 6439 (2013/07/26)
Arylboronic acids are gaining increased importance as reagents and target structures in a variety of useful applications. Recently, the palladium-catalyzed synthesis of arylboronic acids employing the atom-economical tetrahydroxydiboron (BBA) reagent has been reported. The high cost associated with palladium, combined with several limitations of both palladium- and copper-catalyzed processes, prompted us to develop an alternative method. Thus, the nickel-catalyzed borylation of aryl and heteroaryl halides and pseudohalides using tetrahydroxydiboron (BBA) has been formulated. The reaction proved to be widely functional group tolerant and applicable to a number of heterocyclic systems. To the best of our knowledge, the examples presented here represent the only effective Ni-catalyzed Miyaura borylations conducted at room temperature.
