944060-66-6

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Chloro-8-methoxyquinazoline serves as a building block in the synthesis of various pharmaceutical compounds and chemical intermediates. Its unique structure and functional groups contribute to the development of new drugs with improved therapeutic properties.
Used in Medical Research:
In the field of medical research, 2-chloro-8-methoxyquinazoline is utilized for its potential applications in drug development. Its pharmacological properties are being investigated to explore its efficacy in treating various diseases and conditions.
Used in Drug Development:
Due to its diverse biological properties, 2-chloro-8-methoxyquinazoline is considered a promising candidate for drug development. Researchers are actively studying its potential therapeutic applications to identify new treatment options for various health issues.

InChI:InChI=1/C9H7ClN2O/c1-13-7-4-2-3-6-5-11-9(10)12-8(6)7/h2-5H,1H3

Upstream product

• 70127-96-7 2-amino-3-methoxy-benzaldehyde 
• 53055-05-3 3-methoxy 2-nitrobenzaldehyde 
• 858452-80-9 8-methoxyquinazolin-2-ol 

Downstream Products

• 953039-10-6 2-chloro-8-hydroxyquinazoline 
• 953039-49-1 tert-butyl 4-((2-chloroquinazolin-8-yl)oxy)piperidine-1-carboxylate 
• 953039-88-8 7-bromo-2,5-dichloro-8-methoxy-quinazoline 
• 953039-87-7 7-bromo-2,5-dichloro-quinazolin-8-ol 
• 953040-03-4 5-bromo-2-chloro-quinazolin-8-ol 
• 953040-09-0 2,5-dichloro-8-methoxy-quinazoline 
• 953039-39-9 C₁₁H₁₁ClN₂O 
• 953040-05-6 tert-butyl 4-(5-bromo-2-(2-chloro-4-morpholin-4-yl-phenylamino)quinazolin-8-yloxy)-piperidine-1-carboxylate 

Relevant academic research and scientific papers

Synthesis and biological studies of new quinazolines with ether functions in position 2

A series of new quinazolines linked to triazoles through an ether chain in position 2 has been designed and synthetized through a flexible route. Cytotoxicity assays on selected cancer cell lines and inhibition studies toward a panel of representative mam

QUINAZOLINES FOR PDK1 INHIBITION

The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

NEUROLOGICALLY-ACTIVE COMPOUNDS

The present invention relates to neurologically-active compounds, being heterocyclic compounds having two fused 6-membered rings with a nitrogen atom at position 1 and a hydroxy or mercapto group at position 8 with at least one ring being aromatic. Also disclosed are processes for the preparation of these compounds and their use as pharmaceutical or veterinary agents, in particular for the treatment of neurological conditions, more specifically neurodegenerative conditions such as Alzheimer's disease.