944127-06-4Relevant academic research and scientific papers
High-quality oligo-RNA synthesis using the new 2′-O-TEM protecting group by selectively quenching the addition of p-tolyl vinyl sulphone to exocyclic amino functions
Zhou, Chuanzheng,Pathmasiri, Wimal,Honcharenko, Dmytro,Chatterjee, Subhrangsu,Barman, Jharna,Chattopadhyaya, Jyoti
, p. 293 - 301 (2007)
During the F--promoted deprotection of the oligo-RNA, synthesized using our 2′-O-(4-tolylsulfonyl)ethoxymethyl (2′-O-TEM) group [Org. Biomol. Chem. 5, 333 (2007)], p-tolyl vinyl sulphone (TVS) is formed as a by-product. The TVS formed has been
