94426-69-4 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(4-hydroxy-2-oxobutyl)-5-methylpyrimidine-2,4(1H,3H)-dione is used as a key intermediate in the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Organic Chemistry:
In the field of organic chemistry, 1-(4-hydroxy-2-oxobutyl)-5-methylpyrimidine-2,4(1H,3H)-dione serves as a valuable building block for the preparation of novel molecules. Its versatile chemical properties enable the creation of a wide range of compounds with diverse applications.
Used in Medicinal Chemistry:
1-(4-hydroxy-2-oxobutyl)-5-methylpyrimidine-2,4(1H,3H)-dione has potential applications in the field of medicinal chemistry, where it can be utilized for the development of new drugs and therapeutic agents. Its unique structure and properties make it a promising candidate for further research and development in this area.
Used in the Chemical Industry:
1-(4-hydroxy-2-oxobutyl)-5-methylpyrimidine-2,4(1H,3H)-dione is also used in the chemical industry for the production of various specialty chemicals and materials. Its versatility and reactivity make it a valuable component in the synthesis of a wide range of products.
Check Digit Verification of cas no
The CAS Registry Mumber 94426-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,4,2 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 94426-69:
(7*9)+(6*4)+(5*4)+(4*2)+(3*6)+(2*6)+(1*9)=154
154 % 10 = 4
So 94426-69-4 is a valid CAS Registry Number.
94426-69-4Relevant academic research and scientific papers
Phadtare, Shashikant,Zemlicka, Jiri
, p. 3675 - 3679 (1989)
Attempted isomerization of N1-(4-hydroxy-2-butyn-1-yl)thymine (3d) with 0.1 M NaOH at 100 deg C led to acetonylthymine (8) instead of thymallene (1d).In 1 M NaOH compound 3d afforded oxacyclopentene 9d, whereas reaction with 1,5-diazabicyclonon-5-ene (DBN) in dimethylformamide (DMF) gave cyclic imino ether 11.Hydrolysis of 11, effected by 0.1 M NaOH, furnished β-hydroxy ketone 12.At 100 deg C both 11 and 12 yielded 8.The results are explained in terms of ionization of thymine base relative to that of alcoholic hydroxy group of 3d or putative intermediate 1d.Acetoxybutynol 16 was transformed with potassium tert-butoxide (tBuOK) in DMF to butenyne 17.Protection of 16 with methyl (SEM) group led to compound 19.Ammonolysis of 19 gave SEM derivative 20, which was isomerized with tetrabutylammonium fluoride in tetrahydrofuran to protected thymallene 21.The latter was deblocked with SnCl4 in CH2Cl2 to give thymallene (1d).Attempted isomerization of 19 or 20 with tBuOK in DMF led only to elimination of SEM-substituted thymine.
